It’s been 30 years now from the first human baby from frozen egg cells. When in 1986. 42-year-old women showed up in a clinic where she had a few options of becoming a parent: egg freezing, embryo freezing, egg donation program and adoption. What nowadays is a big market was just an experiment on a few, with the methodology different than the one used now. Older slow freeze method had lower success rates than modern egg freezing. The older, conventional freezing methods could result in ice crystal formation making the egg cell fragile and less suitable for handling. Eggs belong to the most delicate cells in the body – they are big and filled with sensitive materials.

Oocyte cryopreservation (egg freezing, vitrification) is a method to preserve ones fertility and beat up the biological clock for many years, possibly even a whole decade or longer. This is an attractive option for women pursuing their careers, or the ones who haven’t found a partner yet. They can freeze eggs in their 20’s and later, when they feel ready to have a family, those eggs can be thawed and fertilized. The most positive fact with egg freezing is that the woman remains genetic parent.

However,  keep in mind that this is a unique case of a live birth at the age of 46 after IVF using egg cells that were cryopreserved 3 years earlier. The prognosis for a live birth from IVF in a patient with very advanced reproductive age remains poor and this case should be interpreted with caution so as to not provide false hope to women aged 35 and above.

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